Publication detail

Computer modelling of effect of transversal tubules on excitation - contraction coupling in cardiac cells (Basic study).

PÁSEK, M. CHRISTÉ, G. ŠIMURDA, J.

English title

Computer modelling of effect of transversal tubules on excitation - contraction coupling in cardiac cells (Basic study).

Type

conference paper

Language

en

Original abstract

The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many resent experimental works it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. The aim of our work was to design a mathematical model of electrical activity of cardiac cell including a quantitative description of T-system function and to explore the physio-logical significance of T-system in excitation-contraction coupling quantitatively.

English abstract

The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many resent experimental works it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. The aim of our work was to design a mathematical model of electrical activity of cardiac cell including a quantitative description of T-system function and to explore the physio-logical significance of T-system in excitation-contraction coupling quantitatively.

Keywords in English

cardiac cell, cardiac cell, quantitative modelling

Released

01.01.2001

Publisher

Ústav termomechaniky AV ČR

Location

Svratka

ISBN

80-85918-64-1

Book

Inženýrská mechanika 2001

Pages count

2

BIBTEX


@inproceedings{BUT5882,
  author="Michal {Pásek} and Georges {Christé} and Jiří {Šimurda},
  title="Computer modelling of effect of transversal tubules on excitation – contraction coupling in cardiac cells (Basic study).",
  booktitle="Inženýrská mechanika 2001",
  year="2001",
  month="January",
  publisher="Ústav termomechaniky AV ČR",
  address="Svratka",
  isbn="80-85918-64-1"
}