Publication detail
Comparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigs
URBANOVÁ, L. SRNEC, R. PROKS, P. STEHLÍK, L. FLORIAN, Z. NÁVRAT, T. NEČAS, A.
Czech title
Srovnácí studie odolnost vůči ohybu dlahy 4.5 LCP Plate-rod Construct tyč a 4.5 LCP Alone aplikované na porušený femur prasete
English title
Comparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigs
Type
journal article - other
Language
en
Original abstract
The study deals with the determination of mechanical properties, namely resistance to bending forces, of flexible buttress osteosynthesis using two different bone-implant constructs stabilizing experimental segmental femoral bone defects (segmental ostectomy) in a miniature pig ex vivo model using 4.5 mm titanium LCP and a 3 mm intramedullary pin ("plate and rod" construct) (PR-LCP), versus the 4.5 mm titanium LCP alone (A-LCP). The "plate and rod" fixation (PR-LCP) of the segmental femoral defect is significantly more resistant (p < 0.05) to bending forces (200 N, 300 N, and 500 N) than LCP alone (A-LCP). Stabilisation of experimental segmental lesions of the femoral diaphysis in miniature pigs by flexible bridging osteosynthesis 4.5 mm LCP in combination with the "plate and rod" construct appears to be a suitable fixation of non-reducible fractures where considerable strain of the implants by bending forces can be assumed. These findings will be used in upcoming in vivo experiments in the miniature pig to investigate bone defect healing after transplantation of mesenchymal stem cells in combination with biocompatible scaffolds.
Czech abstract
Studie se zabývá stanovením mechanických vlastností, zejména odolnost vůči ohybu, pružné opěrné osteosyntézy s použitím dvou různých kostních implantátů (4.5 mm titanium LCP a 3 mm drát, 4.5 mm titanium LCP bez drátu). Implantát stabilizuje porušenou stehenní kost.
English abstract
The study deals with the determination of mechanical properties, namely resistance to bending forces, of flexible buttress osteosynthesis using two different bone-implant constructs stabilizing experimental segmental femoral bone defects (segmental ostectomy) in a miniature pig ex vivo model using 4.5 mm titanium LCP and a 3 mm intramedullary pin ("plate and rod" construct) (PR-LCP), versus the 4.5 mm titanium LCP alone (A-LCP). The "plate and rod" fixation (PR-LCP) of the segmental femoral defect is significantly more resistant (p < 0.05) to bending forces (200 N, 300 N, and 500 N) than LCP alone (A-LCP). Stabilisation of experimental segmental lesions of the femoral diaphysis in miniature pigs by flexible bridging osteosynthesis 4.5 mm LCP in combination with the "plate and rod" construct appears to be a suitable fixation of non-reducible fractures where considerable strain of the implants by bending forces can be assumed. These findings will be used in upcoming in vivo experiments in the miniature pig to investigate bone defect healing after transplantation of mesenchymal stem cells in combination with biocompatible scaffolds.
Keywords in Czech
Fixaci zlomeniny, tříštivá zlomenina, ostectomie, osteosyntéza, porušení implantátu
Keywords in English
Fracture fixation, comminuted fracture, ostectomy, buttress osteosynthesis, implant failure
RIV year
2010
Released
20.12.2010
Publisher
University of Veterinary and Pharmaceutical Sciences in Brno
Location
Brno
ISSN
0001-7213
Journal
ACTA VETERINARIA BRNO
Volume
79
Number
4
Pages from–to
613–620
Pages count
8
BIBTEX
@article{BUT43431,
author="Lucie {Urbanová} and Robert {Srnec} and Pavel {Proks} and Ladislav {Stehlík} and Zdeněk {Florian} and Tomáš {Návrat} and Alois {Nečas},
title="Comparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigs",
journal="ACTA VETERINARIA BRNO",
year="2010",
volume="79",
number="4",
month="December",
pages="613--620",
publisher="University of Veterinary and Pharmaceutical Sciences in Brno",
address="Brno",
issn="0001-7213"
}