Publication detail

The orientations of rigid glass fibres in turbulent flows inside a replica of human airways

LÍZAL, F. KÁNSKÁ, J. CABALKA, M. MIŠÍK, O. MALÝ, M. CEJPEK, O. BĚLKA, M. JEDELSKÝ, J.

English title

The orientations of rigid glass fibres in turbulent flows inside a replica of human airways

Type

article in a collection out of WoS and Scopus

Language

en

Original abstract

The inhalation of fibers has long been recognized for its potential to induce a range of health-related concerns, primarily stemming from their ability to deeply penetrate the lower regions of the human respiratory system (Aust et al. 2011). However, instead of merely perceiving this behavior as a source of health risks, it presents an intriguing opportunity for the targeted delivery of therapeutic agents to the alveoli. This prospect not only captivates with its potential benefits but also holds significant commercial promise. Addressing this challenge, partly due to the limitations of our existing mathematical and computational models, which struggle to accurately predict the delivered dose for individual patients, and advancing our understanding of fiber dynamics in turbulent flows, this contribution introduces new data acquired within a replica of the human trachea and the first airway bifurcation. The measurements were performed under realistic inhalation conditions.

English abstract

The inhalation of fibers has long been recognized for its potential to induce a range of health-related concerns, primarily stemming from their ability to deeply penetrate the lower regions of the human respiratory system (Aust et al. 2011). However, instead of merely perceiving this behavior as a source of health risks, it presents an intriguing opportunity for the targeted delivery of therapeutic agents to the alveoli. This prospect not only captivates with its potential benefits but also holds significant commercial promise. Addressing this challenge, partly due to the limitations of our existing mathematical and computational models, which struggle to accurately predict the delivered dose for individual patients, and advancing our understanding of fiber dynamics in turbulent flows, this contribution introduces new data acquired within a replica of the human trachea and the first airway bifurcation. The measurements were performed under realistic inhalation conditions.

Keywords in English

fiber; fibre; turbulent flow; human airways; orientation

Released

13.11.2023

Publisher

Czech Aerosol Society

Location

Čeladná

ISBN

978-80-908653-1-0

Book

PROCEEDINGS OF 22ND ANNUAL CONFERENCE OF THE CZECH AEROSOL SOCIETY

Pages from–to

59–60

Pages count

2

BIBTEX


@inproceedings{BUT186897,
  author="František {Lízal} and Jana {Kánská} and Matouš {Cabalka} and Ondrej {Mišík} and Milan {Malý} and Ondřej {Cejpek} and Miloslav {Bělka} and Jan {Jedelský},
  title="The orientations of rigid glass fibres in turbulent flows inside a replica of human airways",
  booktitle="PROCEEDINGS OF 22ND ANNUAL CONFERENCE OF THE CZECH AEROSOL SOCIETY",
  year="2023",
  month="November",
  pages="59--60",
  publisher="Czech Aerosol Society",
  address="Čeladná",
  isbn="978-80-908653-1-0"
}