Publication detail

Feature-overlapper: The tool for DNA analysis overlap

HAVLÍK, J. BRÁZDA, V. STANĚK, K. JEŽEK, M. ŠŤASTNÝ, J.

English title

Feature-overlapper: The tool for DNA analysis overlap

Type

journal article in Web of Science

Language

en

Original abstract

This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.

English abstract

This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.

Keywords in English

DNA; R-loop; G-quadruplex; Annotation

Released

01.05.2023

Publisher

Elsevier

Location

AMSTERDAM

ISSN

2665-9638

Volume

16

Number

5

Pages from–to

1–4

Pages count

4

BIBTEX


@article{BUT183463,
  author="Jan {Havlík} and Václav {Brázda} and Kamil {Staněk} and Michal {Ježek} and Jiří {Šťastný},
  title="Feature-overlapper: The tool for DNA analysis overlap",
  year="2023",
  volume="16",
  number="5",
  month="May",
  pages="1--4",
  publisher="Elsevier",
  address="AMSTERDAM",
  issn="2665-9638"
}