Publication detail

Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

NOVÁK, K. POLZER, S. KŘIVKA, T. VLACHOVSKÝ, R. STAFFA, R. KUBÍČEK, L. LAMBERT, L. BURŠA, J.

Czech title

Korelace mezi transverzálními a ortogonálními maximálními průměry a alternativními prediktory ruptury aneurysmat břišní aorty

English title

Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

Type

journal article in Web of Science

Language

en

Original abstract

Purpose: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and Methods The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax ( Da-o) quantifying the aneurysm angulation, and Spearman’s correlation coefficients between PWS/PWRR – orthoDmax/axialDmax were calculated. Results The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o >= 3mm ). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAAs ( Da-o>=3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs ( Da-o<3). As angulated AAAs represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.

Czech abstract

Účel: Zatím neexistuje žádný standard pro měření maximálního průměru (Dmax) ze snímků počítačové tomografie (CT) ačkoliv rozdíly mezi Dmax vyhodnocených z transverzálních (axialDmax) nebo ortogonálních (orthoDmax) rovin mohou být značné, zvláště pak pro šikmá (ohnutá, zakřivená) abdominální aneurysmata (AAA). Z tohoto důvodu jsme analyzovali jejich korelace s alternativními ukazateli jako je maximální napětí (PWS) nebo maximální riziko ruptury (PWRR) abychom rozhodli, který ze zmíněných průměrů je více relevantní pro posouzení rizika ruptury AAA. Materiál a metody Hodnoty Dmax byly měřeny školeným rediologem z celkově 70ti snímků CT a odpovídající PWS a PWRR byly vyhodnoceny pomocí metody konečných prvků (FEA). Kohorta byla seřazena podle rozdílů mezi axialDmax a orthoDmax (Da-o) určující míru šikmosti AAA, následně byly vypočteny korelační (Spearman) korelační koeficienty mezi PWS/PWRR – orthoDmax/axialDmax. Výsledky Korelace PWS/PWRR vs. orthoDmax byly podstatně vyšší u šikmých AAA (s Da-o >= 3mm). Pod tímto limitem korelace byla téměř stejná pro obě hodnoty Dmax. Analýza AAA, která byla rozdělana dvě skupina – šikmá (n=38) a rovná (n=32), odhalila, že tyto obě skupiny jsou si podobné téměř ve všech parametrech (orthoDmax, PWS, PWRR) až na axialDmax (p=0.024) Závěry Bylo potvrzeno, že orthoDmax lépe koreluje s alternativními prediktory PWS a PWRR pro šikmá AAA (Da-o>=3) zatímco nebyl zaznamenám téměř žádný rozdíl mezi orthoDmax a axialDmax u rovných AAA (tj. Da-o < 3mm). Pokud aneurysmata representují podstatnou část případů, může být doporučeno použít orthoDmax jako jedinný Dmax parametr pro vyhodnocení rizika ruptury AAA.

English abstract

Purpose: There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and Methods The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax ( Da-o) quantifying the aneurysm angulation, and Spearman’s correlation coefficients between PWS/PWRR – orthoDmax/axialDmax were calculated. Results The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o >= 3mm ). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAAs ( Da-o>=3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs ( Da-o<3). As angulated AAAs represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.

Keywords in Czech

Aneurysma břišní aorty; Korelační analýza, maximální průměr, maximální napětí, maximální riziko ruptury

Keywords in English

Abdominal aortic aneurysm; Correlation analysis, Maximal diameter, Peak wall stress, Peak wall rupture risk

Released

01.04.2017

Publisher

Elsevier

Location

Amsterdam, Nizozemsko

ISSN

0010-4825

Volume

83

Number

3

Pages from–to

151–156

Pages count

6

BIBTEX


@article{BUT134010,
  author="Kamil {Novák} and Stanislav {Polzer} and Tomáš {Křivka} and Robert {Vlachovský} and Robert {Staffa} and Luboš {Kubíček} and Lukáš {Lambert} and Jiří {Burša},
  title="Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors",
  year="2017",
  volume="83",
  number="3",
  month="April",
  pages="151--156",
  publisher="Elsevier",
  address="Amsterdam, Nizozemsko",
  issn="0010-4825"
}