Detail publikace

Effect of modulation of ionic channel conductivities on restitution processes in cardiac cells (Computer modelling).

PÁSEK, M. ŠLICHTA, J.

Anglický název

Effect of modulation of ionic channel conductivities on restitution processes in cardiac cells (Computer modelling).

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

en

Originální abstrakt

The restitution properties of cardiac action potential were shown to be important determinants of stability of reentrant arrhythmias. The restitution hypothesis states that steeply sloped restitution curves (relations between action potential duration and preceding diastolic interval) induce unstable wave propagation that results in wave break, the event that leads to fibrillation. In this contribution we try to explore the effect of modulation of membrane channel conductuvities on electrical restitution curves by means of computer modelling.

Anglický abstrakt

The restitution properties of cardiac action potential were shown to be important determinants of stability of reentrant arrhythmias. The restitution hypothesis states that steeply sloped restitution curves (relations between action potential duration and preceding diastolic interval) induce unstable wave propagation that results in wave break, the event that leads to fibrillation. In this contribution we try to explore the effect of modulation of membrane channel conductuvities on electrical restitution curves by means of computer modelling.

Klíčová slova anglicky

cardiac cell, electrical restitution

Vydáno

01.01.2001

Nakladatel

Institute of Solid Mechanics, Faculty of Mechanical Engineer

Místo

Třešť

ISBN

80-7204-207-6

Kniha

Mechatronics robotics and biomechanics

Počet stran

2

BIBTEX


@inproceedings{BUT5883,
  author="Michal {Pásek} and Jiří {Šlichta},
  title="Effect of modulation of ionic channel conductivities on restitution processes in cardiac cells (Computer modelling).",
  booktitle="Mechatronics robotics and biomechanics",
  year="2001",
  month="January",
  publisher="Institute of Solid Mechanics, Faculty of Mechanical Engineer",
  address="Třešť",
  isbn="80-7204-207-6"
}