Detail publikace
Tensegritní struktury a jejich použití v modelech cytoskeletu
BURŠA, J.
Český název
Tensegritní struktury a jejich použití v modelech cytoskeletu
Anglický název
TENSEGRITY STRUCTURES AND THEIR APPLICATION IN MODELS OF CYTOSKELETON
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
en
Originální abstrakt
Investigation of principles of mechanotransduction in living animal cells creates a basis for understanding processes in cardio-vascular system such as tissue remodelation, atherosclerotic changes, growth of aneurysms, etc. To be able to estimate the biochemical response of the cell or tissue on a mechanical load, we need to determinate the very quantity (or set of quantities) that is responsible for this response. As cell is a complex structure with numerous components, it cannot be expected that this quantity will be found on the base of homogeneous continuum models. Therefore more complex (structural) finite element models of the mechanical behaviour of cells are needed. A new more realistic model of cytoskeleton has been created. The model should be able to simulate various mechanical tests of isolated cells. In future various types of tests carried out with the same type of cells (vascular smooth muscle cells) should be simulated with the aim to identify constitutive parameters of the individual components of the model.
Český abstrakt
Článek vysvětluje pojem tensegritní struktury a na příkladech ukazuje pravidla pro jejich tvorbu. Na základě těchto pravidel pak je vytvořen nový model cytoskeletu živočišné buňky.
Anglický abstrakt
Investigation of principles of mechanotransduction in living animal cells creates a basis for understanding processes in cardio-vascular system such as tissue remodelation, atherosclerotic changes, growth of aneurysms, etc. To be able to estimate the biochemical response of the cell or tissue on a mechanical load, we need to determinate the very quantity (or set of quantities) that is responsible for this response. As cell is a complex structure with numerous components, it cannot be expected that this quantity will be found on the base of homogeneous continuum models. Therefore more complex (structural) finite element models of the mechanical behaviour of cells are needed. A new more realistic model of cytoskeleton has been created. The model should be able to simulate various mechanical tests of isolated cells. In future various types of tests carried out with the same type of cells (vascular smooth muscle cells) should be simulated with the aim to identify constitutive parameters of the individual components of the model.
Klíčová slova anglicky
Keywords: Tensegrity, cytoskeleton, mechanotransduction, finite element model
Rok RIV
2006
Vydáno
13.11.2006
Nakladatel
Brno University of Technology, Institute of Solid mechanics, Mechatronics and Biomechanics
Místo
Hrotovice
ISBN
80-214-3232-2
Kniha
Human Biomechanics 2006
Časopis
Nezařazené články
Strany od–do
68–69
Počet stran
8
BIBTEX
@inproceedings{BUT24562,
author="Jiří {Burša},
title="TENSEGRITY STRUCTURES AND THEIR APPLICATION IN MODELS OF CYTOSKELETON",
journal="Nezařazené články",
booktitle="Human Biomechanics 2006",
year="2006",
month="November",
pages="68--69",
publisher="Brno University of Technology, Institute of Solid mechanics, Mechatronics and Biomechanics",
address="Hrotovice",
isbn="80-214-3232-2"
}