Detail publikace

Tensegrita Princip založený výpočtový model cytoskeletu

BANSOD, Y. BURŠA, J.

Český název

Tensegrita Princip založený výpočtový model cytoskeletu

Anglický název

Tensigrity Principle Based Computational Model of Cytoskeleton.

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

en

Originální abstrakt

The cytoskeleton plays a vital role in intracellular transmission of mechanical signals. The computational model of cytoskeleton based on tensegrity principle presented here has tension supporting cables representing microfilaments, compression supporting struts representing microtubules and springs in tension representing intermediate filaments. The nucleoskeleton and centrosome modelled as self-stabilised regular truncated tensegrity structures aimed to withstand high prestress. Integrins connecting cell with extracellular matrix are also considered to define cell behaviour in vivo. In this way, a more realistic computational model of cytoskeleton for different cell types could be designed for better understanding of respective cell motility and intracellular transmission of mechanical signals.

Český abstrakt

Tento článek popisuje modelovací přístupy pro mikrostruktury částí živých buněk.

Anglický abstrakt

The cytoskeleton plays a vital role in intracellular transmission of mechanical signals. The computational model of cytoskeleton based on tensegrity principle presented here has tension supporting cables representing microfilaments, compression supporting struts representing microtubules and springs in tension representing intermediate filaments. The nucleoskeleton and centrosome modelled as self-stabilised regular truncated tensegrity structures aimed to withstand high prestress. Integrins connecting cell with extracellular matrix are also considered to define cell behaviour in vivo. In this way, a more realistic computational model of cytoskeleton for different cell types could be designed for better understanding of respective cell motility and intracellular transmission of mechanical signals.

Klíčová slova česky

buněčné mechanika, výpočtové modely, Tensegrita, cytoskelet

Klíčová slova anglicky

Cell mechanics, computational models, Tensegrity, Cytoskeleton

Rok RIV

2014

Vydáno

15.07.2014

Nakladatel

6th World Conference on Structural Control and Monitoring (6WCSCM).

Místo

Barcelona, Spain

ISBN

978-84-942844-5-8

Kniha

6th World Conference on Structural Control and Monitoring (6WCSCM)

Strany od–do

3317–3326

Počet stran

10

BIBTEX


@inproceedings{BUT116147,
  author="Yogesh Deepak {Bansod} and Jiří {Burša},
  title="Tensigrity Principle Based Computational Model of Cytoskeleton.",
  booktitle="6th World Conference on Structural Control and Monitoring (6WCSCM)",
  year="2014",
  month="July",
  pages="3317--3326",
  publisher="6th World Conference on Structural Control and Monitoring (6WCSCM).",
  address="Barcelona, Spain",
  isbn="978-84-942844-5-8"
}