Detail publikace
Tensegrita Princip založený výpočtový model cytoskeletu
BANSOD, Y. BURŠA, J.
Český název
Tensegrita Princip založený výpočtový model cytoskeletu
Anglický název
Tensigrity Principle Based Computational Model of Cytoskeleton.
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
en
Originální abstrakt
The cytoskeleton plays a vital role in intracellular transmission of mechanical signals. The computational model of cytoskeleton based on tensegrity principle presented here has tension supporting cables representing microfilaments, compression supporting struts representing microtubules and springs in tension representing intermediate filaments. The nucleoskeleton and centrosome modelled as self-stabilised regular truncated tensegrity structures aimed to withstand high prestress. Integrins connecting cell with extracellular matrix are also considered to define cell behaviour in vivo. In this way, a more realistic computational model of cytoskeleton for different cell types could be designed for better understanding of respective cell motility and intracellular transmission of mechanical signals.
Český abstrakt
Tento článek popisuje modelovací přístupy pro mikrostruktury částí živých buněk.
Anglický abstrakt
The cytoskeleton plays a vital role in intracellular transmission of mechanical signals. The computational model of cytoskeleton based on tensegrity principle presented here has tension supporting cables representing microfilaments, compression supporting struts representing microtubules and springs in tension representing intermediate filaments. The nucleoskeleton and centrosome modelled as self-stabilised regular truncated tensegrity structures aimed to withstand high prestress. Integrins connecting cell with extracellular matrix are also considered to define cell behaviour in vivo. In this way, a more realistic computational model of cytoskeleton for different cell types could be designed for better understanding of respective cell motility and intracellular transmission of mechanical signals.
Klíčová slova česky
buněčné mechanika, výpočtové modely, Tensegrita, cytoskelet
Klíčová slova anglicky
Cell mechanics, computational models, Tensegrity, Cytoskeleton
Rok RIV
2014
Vydáno
15.07.2014
Nakladatel
6th World Conference on Structural Control and Monitoring (6WCSCM).
Místo
Barcelona, Spain
ISBN
978-84-942844-5-8
Kniha
6th World Conference on Structural Control and Monitoring (6WCSCM)
Strany od–do
3317–3326
Počet stran
10
BIBTEX
@inproceedings{BUT116147,
author="Yogesh Deepak {Bansod} and Jiří {Burša},
title="Tensigrity Principle Based Computational Model of Cytoskeleton.",
booktitle="6th World Conference on Structural Control and Monitoring (6WCSCM)",
year="2014",
month="July",
pages="3317--3326",
publisher="6th World Conference on Structural Control and Monitoring (6WCSCM).",
address="Barcelona, Spain",
isbn="978-84-942844-5-8"
}