Detail publikace

CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION

JADRNÁ, L. GUMULEC, J. BURŠA, J.

Anglický název

CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION

Typ

článek ve sborníku mimo WoS a Scopus

Jazyk

en

Originální abstrakt

Cellular mechanics undergo complex changes during cancer progression in parallel with metabolic reprogramming due to altered demands on its motility. As the cytoskeleton forms a major part of cellular stiffness, this study focuses mainly on exploring cytoskeletal changes in cancer cells and evaluating their direct impact on cellular stiffness. However, the association between cellular stiffness and tumor cell aggressiveness is not straightforward and results vary depending on tumor type. The main aim of this study was to explore the relationship between the altered inner structural arrangement and cell aggressivity in prostate cancer cells using a combination of laboratory and computational methods.

Anglický abstrakt

Cellular mechanics undergo complex changes during cancer progression in parallel with metabolic reprogramming due to altered demands on its motility. As the cytoskeleton forms a major part of cellular stiffness, this study focuses mainly on exploring cytoskeletal changes in cancer cells and evaluating their direct impact on cellular stiffness. However, the association between cellular stiffness and tumor cell aggressiveness is not straightforward and results vary depending on tumor type. The main aim of this study was to explore the relationship between the altered inner structural arrangement and cell aggressivity in prostate cancer cells using a combination of laboratory and computational methods.

Klíčová slova anglicky

CELLULAR STIFFNESS; CANCER-INDUCED CYTOSKELETON; CELLULAR MECHANICS

Vydáno

09.07.2023

Nakladatel

ESB

Místo

Maastricht

Kniha

ESB 2023 BOOK OF ABSTRACTS

Číslo edice

28

Počet stran

1

BIBTEX


@inproceedings{BUT184929,
  author="Lucie {Jadrná} and Jaromír {Gumulec} and Jiří {Burša},
  title="CHANGES IN CELLULAR STIFFNESS RELATED TO CANCER-INDUCED CYTOSKELETON REORGANIZATION",
  booktitle="ESB 2023 BOOK OF ABSTRACTS",
  year="2023",
  month="July",
  publisher="ESB",
  address="Maastricht"
}