Detail publikace
Kontinuální modely mechaniky buňky
BANSOD, Y. BURŠA, J.
Český název
Kontinuální modely mechaniky buňky
Anglický název
Continuum-based modeling approaches to cell mechanics.
Typ
článek v časopise - ostatní, Jost
Jazyk
en
Originální abstrakt
The quantitative study of cell mechanics is of paramount interest, since it regulates the behavior of the living cells in response to the myriad of extracellular and intracellular mechanical stimuli. The novel experimental techniques together with robust computational approaches have given rise to new theories and models, which describe cell mechanics as combination of biomechanical and biochemical processes. This review paper encapsulates the existing continuum-based computational approaches that have been developed for interpreting the mechanical responses of living cells under different loading and boundary conditions. The salient features and drawbacks of each model are discussed from both structural and biological points of view. This discussion can contribute to the development of even more precise and realistic computational models of cell mechanics based on continuum approaches or on their combination with microstructural approaches, which in turn may provide a better understanding of mechanotransduction in living cells.
Český abstrakt
Příspěvek pojednává o modelech mechaniky buňky na základě přístupů založených na mechanice kontinua.
Anglický abstrakt
The quantitative study of cell mechanics is of paramount interest, since it regulates the behavior of the living cells in response to the myriad of extracellular and intracellular mechanical stimuli. The novel experimental techniques together with robust computational approaches have given rise to new theories and models, which describe cell mechanics as combination of biomechanical and biochemical processes. This review paper encapsulates the existing continuum-based computational approaches that have been developed for interpreting the mechanical responses of living cells under different loading and boundary conditions. The salient features and drawbacks of each model are discussed from both structural and biological points of view. This discussion can contribute to the development of even more precise and realistic computational models of cell mechanics based on continuum approaches or on their combination with microstructural approaches, which in turn may provide a better understanding of mechanotransduction in living cells.
Klíčová slova česky
Mechanika buňky, výpočtové modely, kontinuální přístup, mechanické modely
Klíčová slova anglicky
Cell mechanics, computational models, continuum approach, mechanical models
Rok RIV
2015
Vydáno
17.09.2015
Nakladatel
World Academy of Science, Engineering and Technology, International Science
Místo
Rome, Italy
ISSN
1307-6892
Kniha
17th International Conference on Cell and Stem Cell Engineering.
Ročník
2
Číslo
9
Strany od–do
1202–1213
Počet stran
12
BIBTEX
@article{BUT115976,
author="Yogesh Deepak {Bansod} and Jiří {Burša},
title="Continuum-based modeling approaches to cell mechanics.",
booktitle="17th International Conference on Cell and Stem Cell Engineering.",
year="2015",
volume="2",
number="9",
month="September",
pages="1202--1213",
publisher="World Academy of Science, Engineering and Technology, International Science",
address="Rome, Italy",
issn="1307-6892"
}